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Patients with GERD are recommended to undergo a diagnostic examination every six months. Particular attention should be paid when determining gastroesophageal reflux disease in children. Take care of yourself and be always healthy! Patients with complaints of heartburn and discomfort during the passage of prevacid 30mg pills through the esophagus are diagnosed with GERD. What it is? This abbreviation stands for gastroesophageal reflux disease. This is a fairly common disease in gastroenterology, which has a chronic course, requiring long-term, and in some cases lifelong treatment, which improves the quality of life of the patient and serves as a prevention of complications. The code for GERD according to ICD-10 is K21.

Bile reflux into the stomach and then into the esophagus is possible - in this case, they speak of duodenogastroesophageal reflux. With them, the alkaline content of the twelveduodenal ulcer (this is lysolecithin, trypsin, bile acids). Such refluxes are possible when the pyloric and esophageal sphincters fail and the contents of the duodenum enter the stomach and reach the esophagus.

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In patients with diseases of the gastrointestinal tract (mainly the upper sections), the reflux of duodenal contents becomes permanent and causes more severe esophagitis than acid reflux. There is also evidence for the role of duodenal reflux in Barrett's esophagus. This formidable complication of GERD is considered as a disease with a high risk of transition to adenocarcinoma of the esophagus.

With both reflux, the patient is worried about heartburn and discomfort in the esophagus. Single episodes of heartburn are often not considered a serious symptom by patients, however, with regular reflux into the esophagus, 10% of patients develop reflux esophagitis - a consequence of reflux in the form of inflammation of the mucosa and even its damage (erosion and hemorrhage, ulcers).

The degree of damage to the esophageal mucosa depends on the composition of the reflux, its duration and resistance of the mucosa (presence of protective factors). Erosions and ulcers of the esophagus are difficult to treat.

If the timing of scarring of duodenal ulcers is 3-4 weeks, stomach ulcers up to 6 weeks, then the healing of esophageal erosions can last 8-12 weeks, and after stopping the medication, a relapse of the disease often occurs.

Dysfunction of the sphincter is often combined with anomalies (short esophagus) and hiatal hernia. The mechanism of reflux is associated with the difference in pressure in the stomach (it is greater) and the esophagus, which, in conditions of dysfunction of the sphincter, contributes to constant reflux.

The patient has symptoms of the disease and erosion in the esophagus is determined. This form occurs in 35% of patients. non-erosive form. There are characteristic symptoms, changes in pH-metry, no erosion. This form is observed in 60% of all patients. Barrett's esophagus.

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Occurs in 5% of cases. Separately, functional heartburn is considered - a condition in which there are symptoms, but there are no changes in pH-metry and changes in the esophagus. Reflux esophagitis is detected during endoscopic examination, therefore, according to endoscopic classification, there are. Simple (catarrhal) esophagitis. Erosive. Ulcers of the esophagus.

At grade 1, single erosions can be detected, occupying up to 10% of the area of the esophagus. There is widespread hyperemia of the distal section with fibrinous plaque.

Erosions merge and capture 50% of the surface. Third degree. Multiple erosions located circularly (around the entire circumference of the esophagus) and occupying the entire surface of the distal mucosa. Contact vulnerability of the mucosa and the spread of inflammation to the thoracic region are noted. Fourth degree.

It is characterized by ulcerative lesions, narrowing of the lumen of the esophagus (this makes it difficult to conduct an endoscope and examine its underlying sections), the development of Barrett's esophagus (esophageal metaplasia).

In general, the integrity of the esophageal mucosa is determined by the balance between aggressive factors and the ability of the mucosa to withstand damaging factors. A protective barrier is a layer of mucus that contains mucin and covers the epithelium of the esophagus.

The mucus layer helps to restore the pH in the esophagus when aggressive refluxants enter. Violation of the mucous layer impairs the cleansing of the esophagus from pathological acidic or alkaline contents, and inflammation occurs in the mucosal epithelium, the severity of which is different - from superficial to the appearance of erosions and ulcers.

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Non-erosive esophagitis, despite the absence of changes in the esophagus, as mentioned above, has a high prevalence and significantly affects the quality of life of the patient. Esophagitis resulting from reflux may be superficial, catarrhal, and erosive. Superficial reflux esophagitis is characterized by minimal mucosal changes. The main endoscopic sign that characterizes superficial esophagitis is the opacity of the mucosa, which is associated with initial changes in it. Catarrhal reflux esophagitis is manifested by hyperemia (redness) and looseness of prevacid online. Catarrhal is the most common form of esophagitis.

Non-erosive reflux esophagitis, what is it? This is a type of GERD in which the patient has characteristic complaints, but there are no changes in the esophagus during endoscopic examination.

With continued refluxes and if untreated, mucin secretion in the mucus is reduced, which is a predisposing factor for erosive reflux esophagitis to occur, which occurs more often in the elderly.

There is a direct relationship between the age of patients and the degree of erosive esophagitis. In addition, it is known that erosive reflux esophagitis is more common in biliary and mixed refluxes, and if they are very frequent and prolonged, the severity of prevacid lesions of the esophagus increases. This form of GERD is difficult to treat and often recurs.

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